2021 Annual Meeting Startup & Practice Management Access Pass-In-Vitro Analysis of Acute Interventions for Post-Traumatic Osteoarthritis

In-Vitro Analysis of Acute Interventions for Post-Traumatic Osteoarthritis

Video Transcription

Video Summary

In this video, Dr. Adam Yankee from Rush University discusses his research on post-traumatic arthritis (PTOA) and potential treatments. He explains that PTOA occurs after acute traumatic injuries and can lead to inflammation and cartilage breakdown. PTOA affects approximately 700,000 adults in the US and costs $6.4 billion to treat annually. Dr. Yankee discusses the potential use of amniotic suspension allograft (ASA) and dehydrated IRAP as treatments for PTOA. He also describes a co-culture model that he used in the lab to study the effects of these treatments on chondrocytes and synovial tissue. The goal of the study is to determine if ASA and IRAP can mitigate the catabolic cascade that occurs after an impact injury to cartilage. This research has the potential to improve treatments for PTOA and benefit cartilage transplant patients.

Asset Caption

Dr. Adam Yanke

Meta Tag

Concept Cartilage

Concept Inflammatory Cascade

Concept Post-traumatic Osteoarthritis

Concept Cartilage Catabolism

Concept Synovium

Keywords

post-traumatic arthritis

PTOA

treatments

amniotic suspension allograft

dehydrated IRAP

Cartilage

Inflammatory Cascade

Post-traumatic Osteoarthritis

Cartilage Catabolism

Synovium