AANA19 Foot & Ankle Access Pass-Preoperative Changes in the Biomarker Profile of the Knee before Anterior Cruciate Ligament (ACL) Reconstruction-Dr. Eric Jason Strauss

Preoperative Changes in the Biomarker Profile of the Knee before Anterior Cruciate Ligament (ACL) Reconstruction-Dr. Eric Jason Strauss

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Video Transcription

Video Summary

In this video, the speaker discusses ACL ruptures, their common causes, and the effects on the articular cartilage. They explain that while ACL reconstruction surgery is successful, recovery and prevention of post-traumatic osteoarthritis vary. The speaker introduces the concept of synovial fluid biomarkers as potential indicators of disease state and targets for treatment. The study presented in the video evaluated changes in biomarker concentrations between the injury and surgery. Significant differences were found in eight out of the ten biomarkers studied. The speaker suggests that monitoring specific biomarkers, such as interleukin 6, may help identify optimal timing for surgery and prevent post-ACL rupture arthritis. The study limitations, ongoing research, and the potential impact on individualized management and reducing complications and post-traumatic osteoarthritis are also discussed. The video concludes with gratitude to the Beaty Family Foundation for their support.

Asset Caption

Concurrent Scientific Session III: Foot and Ankle 5.3.2019

Keywords

ACL ruptures

articular cartilage

synovial fluid biomarkers

post-traumatic osteoarthritis

interleukin 6