APEX Shoulder Mastering Surgical Techniques for Clinical Success-Biologics and Patches: What is the Latest Data? Indications and Technical Pearls

Biologics and Patches: What is the Latest Data? Indications and Technical Pearls

Video Transcription

Video Summary

Dr. Brian Cole discusses rotator cuff tears and the challenges associated with their treatment. He mentions that despite favorable clinical outcomes, there is often a failure of structural integrity in the long term. Factors such as patient age, chronicity, tendons involved, vitamin D levels, bone density, and smoking can contribute to this failure. Dr. Cole also references a study on the metabolomics of the rotator cuff, which indicates metabolic differences between normal and diseased tissue. He emphasizes the importance of structural integrity, listing various studies showing that patients with a healed rotator cuff have greater strength and satisfaction. Dr. Cole then discusses the use of scaffolds and biologics to improve the tendon bone interface and reduce re-tear rates. He mentions the use of scaffolds such as allografts, xenografts, and synthetics, and highlights the success of patch augmentation and extension procedures. He also discusses the use of platelet-rich plasma (PRP) and bone marrow concentrate as biologics, citing studies that show their potential benefits. Dr. Cole concludes by emphasizing the need for further research to understand the multifactorial nature of rotator cuff repair and improve long-term outcomes.

Asset Caption

Brian Cole, MD, MBA

Keywords

rotator cuff tears

structural integrity

scaffolds and biologics

metabolomics study

long-term outcomes