false
OasisLMS
Catalog
Hype, Promise and Reality: Orthopaedic Use of Biol ...
Hype, Promise and Reality: Orthopaedic Use of Biol ...
Hype, Promise and Reality: Orthopaedic Use of Biologics in 2024
Back to course
[Please upgrade your browser to play this video content]
Video Transcription
Video Summary
Platelet-rich plasma (PRP) is discussed in the video for its application in treating tendinopathy and rotator cuff injuries. Studies show varying outcomes, with some positive effects on tendon healing post-rotator cuff repair. Different PRP formulations like leukocyte-rich PRP are recommended for tendinopathy, while other formulations are explored for potential benefits. Precision medicine in biologics is stressed, considering patient responses, cytokine profiles, and dosing accuracy. The complexity of PRP composition, defining biologic targets, and the paracrine mechanism of action in cell-based therapies are also highlighted. Despite outcome variability and the need for more data, PRP shows promise in improving tendon healing. FDA regulations on orthobiologics are discussed, emphasizing the differences between minimally manipulated 361 products and complex 351 products. Healthcare providers are reminded of the importance of understanding regulations to avoid legal issues and to ensure compliance. Staying informed and using reputable resources like the AAOS Orthopedic Biologic website is advised for incorporating cell-based therapies into practice.
Asset Caption
Stephen C. Weber, M.D., Moderator | Scott A. Rodeo, M.D. | Kenneth R. Zaslav, M.D. | Jason L. Dragoo, M.D., FAANA
Keywords
Platelet-rich plasma
PRP
tendinopathy
rotator cuff injuries
tendon healing
precision medicine
biologics
cytokine profiles
dosing accuracy
orthobiologics
FDA regulations
×
Please select your language
1
English