Hype, Promise, and Reality Orthopedic Use of Biologics (2021 Annual Meeting)-Hype, Promise, and Reality: Orthopedic Use of Biologics in 2021'-Rodeo

Video Transcription

Video Summary

In the video, the speaker discusses the potentials and current limitations of orthobiologics, focusing on cell therapy and platelet-rich plasma (PRP). They emphasize the importance of using precise terminology and proper definitions when discussing stem cells and other cell therapies. The speaker highlights the broad field of regenerative medicine, which includes not only cells and PRP but also cytokines, peptides, and matrix scaffolds. They acknowledge the fast-moving and confusing nature of the field and caution against indiscriminate use of these therapies without sufficient evidence. <br /><br />The speaker then delves into the use of PRP and cell therapy for tendinopathy and rotator cuff repair. They present conflicting data on the efficacy of these treatments, with some studies showing positive effects on symptoms and healing while others show no significant difference compared to control treatments or even negative effects. They discuss the heterogeneity in PRP formulations and highlight the need for further research to determine the most effective protocols. The speaker also briefly touches on other factors that may impact tendon healing, such as vitamin D levels, PTH injections, statin therapy, and lifestyle factors like obesity and smoking. They stress the importance of exercising leadership in the field and approaching these treatments with caution and evidence-based practice.

Asset Caption

Dr. Scott A. Rodeo

Keywords

video

orthobiologics

cell therapy

platelet-rich plasma

regenerative medicine

stem cells