Specialized Toolkit Series: ACL Reconstruction-Biologic Augmentation of ACL Reconstruction: Lessons Learned Pre-Clinical and Clinical Study

Biologic Augmentation of ACL Reconstruction: Lessons Learned Pre-Clinical and Clinical Study

Video Transcription

Video Summary

Adam Anz, a surgeon at the Andrews Institute, discusses biological augmentation in ACL reconstruction. He uses translational medicine to explain the process, referencing both preclinical and clinical studies. Anz highlights various studies, pointing out that neither PRP nor cellular therapies currently support ACL reconstruction augmentation. He details his team's techniques and experimental approaches, including a Bio-ACL technique using bone marrow aspirate and scaffolds. Their trials showed no significant improvement but hint at potential benefits. The team continues exploring ACL stump tissues for future improvements. Anz's ongoing research aims to refine and validate biological methods for better ACL graft integration.

Asset Caption

Adam Anz, M.D.
Andrews Institute Orthopaedics & Sports Medicine
Gulf Breeze, Florida

Keywords

ACL reconstruction

biologic augmentation

Bio-ACL technique

graft maturation

cellular therapies

biological augmentation

translational medicine

PRP